e.hormone environmental signaling epigenetics lead in the environmental

About Us

e.hormone is a central conduit providing accurate, timely information and educational resources at the cutting edge of environmental signaling research. The site is part of the Environmental Signaling Network (ESN), a multifaceted program that aims to integrate the vast interdisciplinary signaling field by fostering communication and promoting scientific advancements.

Environmental signaling encompasses the many ways plants and animals use chemical signals to communicate life-driving information, to respond to physical or biological stimuli, and to talk to each other. The internal and external signals police interactions within and between cells and organs as well as among individuals and species. Sometimes, certain natural compounds and synthetic chemicals incorrectly trigger signaling mechanisms – turning them on and off at the wrong times or changing signal intensity that may affect reproduction and health. Endocrine disruption is one of the most studied areas of inadvertent environmental signaling.

Endocrine disrupting chemicals (EDCs) – the pesticides, plasticizers, pharmaceuticals, and other pollutants that interfere with estrogen and other hormone system signals – can affect cells to ecosystems and invertebrates to vertebrates. Humans and animals are exposed to EDCs through food, water, and air and can experience health effects ranging from subtle changes in blood hormone levels to overt reproductive abnormalities, infertility, and cancer. Facing the most risk are women of childbearing age, due to increased exposure through lifestyle choices, and infants and children, due to their small size, higher exposure, and fast growth.

Original support for e.hormone web site was provided by the W. Alton Jones Foundation in 1995. Subsequent funding from the Office of Naval Research, the National Science Foundation, and the Department of Energy is gratefully acknowledged. Current support derives from the Weatherhead Foundation
and the Department of Pharmacology, Tulane University School of Medicine.

The original site design and concept were crafted by John McLachlan and John Vassilopoulos in collaboration with Lou Guillette while he was on sabbatical leave in the Environmental Signaling Group at Tulane University. An informal advisory group over the years has also included, Tyrone Hayes, Wendy Hessler, Taisen Iguchi, and Christopher McLachlan.

Copyright and Credits

Pages and content contained within the e.hormone web site are copyright © 1996-2017 Tulane University, 1430 Tulane Avenue SL-83, New Orleans, Louisiana, U.S.A. (Phone: 504-988-6693).

We encourage the use of the text, diagrams and pictures in whole or in part for educational purposes only with credit given to the CBR and any original authors, illustrators and photographers notates. The commercial use or broader distribution is prohibited. Any reproduction, re-publication or other use is strictly forbidden without the express written permission of the original author.

John McLachlan John A. McLachlan, Ph.D.
Professor of Pharmacology, Tulane University School of Medicine
Adjunct Professor of Ecology and Evolutionary Biology, Tulane University School of Science & Engineering
Celia Scott and Albert J Weatherhead III Distinguished Professor of Environmental Studies
William Toscano William Toscano, Ph.D.
Professor, Division of Environmental Health Sciences, School of Public Health
University of Minnesota
John Vassilopoulos John Vassilopoulos, M.S.
Partner and CIO
IatroDesign, LLC


Link to Schoolzone Site Congratulations on all the work your organization does researching and raising awareness about environmental exposures and toxins and the impact they can have on men, women, and families. We at the Association of Reproductive Health Professionals <http://www.arhp.org/>  (ARHP) are very excited to be part of the discussion about how we can reduce these impacts and improve health for individuals and families.
Link to Schoolzone Site Schoolzone, UK's most active teacher community with over 80,000 registered users, 2300 fully-profiled teacher consultants and thousands of online users has awarded e.hormone.tulane.edu a 5 star rating on their web guide. Here's what they are saying: "This has become a highly comprehensive site on the topic of environmental hormones. The site has links and teaching resources. This site has details which would improve and enhance the amount of knowledge on the impact of hormones on the body and on the environment. Well worth a read."
National Resources Defense Coucil
The National Resources Defense Council picked e.hormone as a featured site, saying "You might know PCBs and phthalates are bad for your health, but do you know why? e.hormone, a website run by the Center for Bioenvironmental Research at Tulane and Xavier Universities, will answer all your questions about environmental chemicals. As the site's tagline proclaims, it is "your gateway to the environment and hormones," providing an up-to-date collection of news, events, research and resources relating to endocrine disrupting chemicals, hormones and the environment."
The Reporter's Environmental Handbook (Rutgers University Press, 2003). The issue briefs section includes information about endocrine disrupters; the first resource listed is the CBR's Environmental Concepts Made Easy site (now e.hormone).
NAST's sciLINKS selected our endocrine system pages as a textbook supplement.
Our pages "provide an eclectic collection of information that scientists and nonscientists alike will find of value."   Genetic Engineering News (On the Web), 20(10; 15 May 00):92.
Science Magazine
Science Magazine's NetWatch: Our pages "give a balanced account of what's known, and unknown, about the biological effects of endocrine disruptors."   Science (NetWatch), 287(5453; 28 Jan 2000):543.
A Collection of Evaluated Web Sites. In building a premium collection of evaluated scholarly Web sites, subject specialists in the ISI® editorial department designed a comprehensive selection process modeled on the quality editorial standards developed by ISI over forty years ago.