1. Endocrine Disruptors Potentiate Coactivators: The role of MAPKs, Daniel E. Frigo, Matthew E. Burow, Jawed Alam, and John A. McLachlan
2. AKT and MAPK regulation of ERb-mediated transcription through AF-2 recruitment/activation of p160 Coactivators, Bich N. Duong, Steven Elliott, Lilia I. Melnik, Barbara S. Beckman, Jawed Alam, John A. McLachlan and Matthew E. Burow
3. Expression of Cofactors in Mouse Uterus and Vagina after Stimulation of Diethylstilbestrol or Bisphenol-A, Tomomi Sato and Taisen Iguchi
4. Effect of Neonatal Treatment with Bisphenol-A on the Rat Uterus with Reference to Decidual Response, Ohta, Y., Saishu, N., Ishibashi, T., Iguchi, T
5. The Xenoestrogen Bisphenol-A Stimulates Inappropriate Prostate Cancer Cell Growth and Tumor-Derived Androgen Receptor Activity, Yelena Wetherill, Ann Staubach, Christin Petre, Kelly Monk, Alvaro Puga, Xu-Bao Shi, and Karen E. Knudsen
6. Infantile Exposure to 4-Tert-Octylphenol Interferes with the Rat Ovarian Steroidogenesis, Sari Myllymaki, Marika Karjalainen, Jorma Toppari, Jorma Paranko
7. Diethylstibestrol (DES) induces Abnormal Uterine Differentiation, Wei-Wei Huang, Qun Bi, Jussi Vuoristo, Tung-Chin Chiang, John Mclachlan and Liang MA
8. The Molecular Mechanism of Diethylstilbestrol (DES) -Induced Genital Tract Lesions, Takeshi Kurita, Alea A. Mills and Gerald R. Cunha
9. Stilbene Chemicals: Potential Disrupters of Diverse Signaling Systems, Erica N. Simpson, Jennifer E. Fox, and John A. McLachlan
10. Production And Metabolism Of Bioactive Hydroxy-Estrogens By Target Cancer Cells In Vivo And In Vitro, L. Castagnetta, R. Stefano, V.
11. Vitamin A Modifies the Effects of Perinatal Treatment with Estrogen on the Mouse Genital Tracts, Manabu Matsuda, Fujiko Masui, Keiko Nakahashi, and Takao Mori
12. Long-Term Exposure to b-Hexachlorocyclohexane Promotes Transformation and Invasiveness of MCF7 Human Beast Cancer Cells, Enmin Zou and Fumio Matsumura
13. An Investigation of the Endocrine Disrupting Potential of Organophosphate Pesticides, Shala L. Thomas, Suzanne Nehls and Thomas E. Wiese
14. Xenoestrogenic Compounds from Plastic Containers Bind to Estrogen Receptors a and b (ERa and ERb) and Affect Breast Cancer Cell Proliferation, Sandra Gray, Patilee Tate, Brett Lackey and Susan Gray
15. Interaction Kinetics of Estrogen Receptors with Estrogen Response Elements, Matthewos Eshete and William L. Alworth
16. Evaluation of the Estrogenic Effects of Legume Extracts Containing Phytoestrogens, Stephen M. Boué, Thomas E. Wiese, Suzanne Nehls, Matthew Burow, Steven Elliot, Carol H. Carter-Wientjes, Betty Y. Shih, and Thomas E. Cleveland
Wildlife Exposure and Mechanisms
17. The ING Tumor Suppressor Protein is Regulated by Thyroid Hormone in the Xenopus laevis Tadpole and is Affected by the Herbicide Acetochlor, M.J. Wagner, K. Cheung, K. Werry, and C.C. Helbing
18. Identification of Phosphoproteome Components Important in Thyroid Hormone-Induced Metamorphosis of the Xenopus laevis Tadpole, D. Domanski, and C. C. Helbing
19. Investigation of the Effects of Atrazine on the Gonadal Differentiation in the Hermaphroditic Mangrove Killifish, Rivulus marmoratus, WP Davis, KJ Bogel, G Cripe, B Doheney, A Thiyagarajah, EF Orlando
20. Abnormal Vitellogenin Production in vivo and Alterations of Aromatase Activity in vitro due to Organochlorine Contaminants in Sea Turtles, Jennifer M. Keller, Patricia McClellan-Green
21. Testosterone:Fatty Acid Esterification: A Novel Target of Endocrine Disruption Caused by Tributyltin, Meredith P. Gooding and Gerald A. LeBlanc
22. Effects of a nonylphenol- and phytoestrogen-enriched diet on the production of plasma vitellogenin, steroid hormone, hepatic cytochrome P450 IA and glutathione-S-transferase activities in goldfish, Carassius auratus, K. Arizono, H. Ishibashi, R. Shinkura, M. Yamamoto
23. Identification of Differentially Expressed Genes during Estrogen-Induced Sex- Reversal in Rana Rugosa Tadpoles, Minoru Takase, Taisen Iguchi, John Nielsen, Niels E. Skakkebaek & Henrik Leffers
24. The Androgen Dependent Expression of Secondary Sexual Character in Fish: Gonopodium Formation of Mosquitofish Gambusia affinis, Yukiko Ogino, Hironori Katoh, and Gen Yamada
25. Thyroid Hormones and the Effects of Contaminants in Steller sea lions (Eumetopias jubatus), Matthew J. Myers and Shannon Atkinson
26. Effects of Paper and Pulp Mill Exposure on the Reproductive Physiology of Lepomis macrochirus in Elevenmile Creek, Jeanine R. Burse, Ann O. Cheek, Henry L. Bart, Jr.
27. Gonadotropin and Estrogen Responses in Wild Caught Turtles (Chrysemys picta) from Cape Cod, Massachusetts, Noppadon Kitana, Seung Jae Won and Ian P. Callard
28. Inverted Offspring Sex Ratio in Specific Occupations, El Safty A.M.K., Attia D.I.
29. Total Dioxins and Furans Modify the Association of PCBs with Thyroid Hormones in Adults Consuming Great Lakes Fish, Mary Turyk, Victoria Persky, Henry A. Anderson, Lawrence P Hanrahan, Claire Falk, Dyan N. Steenport , Robert Chatterton, Jr., Jr., Sally Freels, and the Great Lakes Consortium
30. Gynaecological Disturbances Among Females Engaged in the Manufacture of Sex Hormones, El-Samra G.H., Siha M.S., El-Safty A.M.K. Abd-El-Badii M.
31. Is Gulf War Syndrome an Endocrine Disorder?, Cynthia V. Rider and Gerald A. LeBlanc
In Search of New Signals
32. Development of ELISA for Quantitative Analysis for Environmental Hormones, Shigeru Fujimoto, Yasuhiro Goda, Ayako Kobayashi, Masato Hirobe, Michihiko Ike, Masanori Fujita
33. Yeast Oestrogen Assays: a Comparison of Different Reporter Genes and human Oestrogen Receptors a and b, Toine F.H. Bovee, Richard J.R. Helsdingen and Ron L.A.P. Hoogenboom
34. Endocrine Disruptor Studies and Reverse Toxicology, Jun Kanno, Katsuhide Igarashi, Kenichi Aisaki, Atsushi Ono, and Tohru Inoue
35. Choriogenins as Biomarkers for Estrogen-induction in Louisiana wildlife, Gary J. LaFleur, Jr, Christie Landry, Cass Stevens
36. The Effects of Flutamide and Diethylstilbestrol Exposure on the Reproductive Organs and Thyroid of Male Rats by the Rodent 20-day Thyroid/Pubertal Assay, Jae-Ho Shin, Hyung Sik Kim, Hyun Ju Moon, Il Hyun Kang, Tae Sung Kim, Ji Hyun Seok, In Young Kim, and Soon Young Han
37. Modeling Simulations of the Ligand-Receptor Interactions of Environmental Chemicals Bound to the Estrogen Receptor, T. E. Wiese and S. Nehls
38. EPA’s Endocrine Disruptor Screening Program, Greg Schweer and Elaine Francis
Thursday, October 17th
SESSION I: HORMONES AND THE ENVIRONMENT: A GLOBAL PERSPECTIVE
Chair: Akira Arimura (Tulane University) (Web Page), Department of Neuroendocrinology, Tulane University Health Sciences Center, New Orleans, Louisiana
"Discovery of the First Hormone: A Shared Experience Between Japan and New Orleans."
Noboru Takasugi (Yokohama University, Japan), President Emeritus, Yokohama University, Japan
"Impact of Developmental Endocrine Research in Japan."
Terri Damstra (World Health Organization), International Program on Chemical Safety, World Health Organization, Research Triangle Park, North Carolina
"World Health Organization Global Assessment of the State-of-the-Science of Endocrine Disrupting Chemicals"
SESSION II: CELL SIGNALING AND HORMONE ACTION: THE EMERGING PARADIGM
Jan-Ake Gustafsson (Karolinska Institutet, Sweden) (Web Page), Center for Nutrition & Toxicology, Karolinska Institute, Stockholm, Sweden
"Environmental Signals: Multiple Receptors and Multiple Inputs."
David Armstrong (NIEHS) (Web Page), Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina
"Racking Your Brain for Thyroid Hormone: Following an Old Hormone Down a New Pathway."
Trevor Archer (NIEHS) (Web Page), Laboratory of Reproductive and Developmental Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina
"Estrogen-induced Chromatin Remodeling.”
Benita Katzenellenbogen (University of Illinois at Urbana-Champaign), GNOF Distinguished Lecturer on Women's Health and the Environment, Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign
"Estrogen Signaling: The Importance of Molecular Biology in Women’s Health.”
POSTER SESSION and PRE-DINNER RECEPTION
Friday, October 18th
SESSION III: ECOLOGICAL SIGNALS A
Tyrone Hayes (University of California, Berkeley) (Web Page), Department of Integrative Biology, University of California, Berkeley
"The Common Pollutant, Atrazine, Alters the Sexual Development of Male Frogs.”
ECOLOGICAL SIGNALS B
Chair: Eva Oberdoerster, Department of Biology, Southern Methodist University, Dallas, Texas
SESSION IV: CHEMICAL APPROACHES TO ENDOCRINE DISRUPTING CHEMICALS
Chair: Philip Jones, Xavier University, New Orleans, Louisiana
Dana Kolpin, (United States Geological Society), Iowa City
“Inventory of Pharmaceutical Chemicals and Other Biologically Active Pollutants in U.S. Streams and Rivers.”
NEW INVESTIGATION REPORTS
Chair: Joe Thornton, Center for Ecology & Evolutionary Biology, University of Oregon, Eugene
Location: Audubon Tea Room, Audubon Zoo
Entertainment: The Soul Rebels Brass Band
Saturday, October 19th
SESSION V: IN VITRO & IN VIVO MODEL SYSTEMS FOR STUDYING ENDOCRINE DISRUPTION
Carol Swartz (National Institute of Environmental Health Sciences), NIEHS, Research Triangle Park, North Carolina
"Immortalized Human Uterine Cell Lines as Model Systems to Study Hormones and Other Environmental Chemicals."
Yasuhiro Tomooka (National Institute of Agrobiological Resources, Japan), Department of Biological Science and Technology, Tokyo University of Science, Noda, Japan
“Immortalized Mouse Cell Lines from Reproductive Tract and Brain."
Thomas Wiese (Tulane University) (Web Page), Center for Bioenvironmental Research at Tulane & Xavier Universities, New Orleans, Louisiana
"Molecular Determinants of the Estrogen, Androgen, and Progestin Activities of Environmental Hormones."
SESSION VI: RESPONSE TO ECOSYSTEM PERTURBATION
Robert Twilley (University of Louisiana at Lafayette) (Web Page), Center for Ecology and Environmental Technology, University of Louisiana at Lafayette
“From Environmental Hormones to Ecological Habitats: Defining Models of Ecosystem Self-Organization.”
It is the policy of the Center for Continuing Education at Tulane University Health Sciences Center to ensure balance, independence, objectivity and scientific rigor in all its educational programs. All faculty participating in these programs are expected to disclose to the program audiences any real or apparent conflict of interest related to the content of their presentations. This information pertains to relationships with pharmaceutical companies, biomedical device manufacturers or other corporations whose products or services are related to the subject matter of the presentation topic or products in the research and development phase.