Environmental Hormones: Past, Present, Future
A Symposium Marking the 20th Anniversary of the First Meeting of Estrogens in the Environment
October 18-20, 1999
Hosted by: Tulane/Xavier Center for Bioenvironmental Research
Convening 20 years after the first Estrogens in the Environment meeting, the symposium mingled historical perspectives, topic reviews, and latebreaking research into sessions covering hormonal signaling, chemicals as hormones, hormone response mechanisms, developmental toxicology, and future directions. Below are summaries of select presentations.
1. Uterine Response To Estradiol: Low-dose Facilitation And High-dose Inhibition Due To Fetal Exposure to Diethylstilbestrol And Methoxychlor In CD-1 Mice.
LC Alworth, KL Howdeshell, RL Ruhlen, FS vom Saal,Division of Biological Sciences, University of Missouri, Columbia, MO 65211
2. Expression Of AUF1/hnRNP D, A Regulator Of mRNA Degradation, Is Controlled By Estrogen In Rat Uterus.
Y. Arao 1,2, A. Kikuchi 1,2, and F. Kayama 1,2;1, Jichi Medical School, Tochigi, Japan, 2, CREST, JST, Japan
3. Soybean Phytoestrogens: Quantitation And The Accumulation Of Isoflavonoid Phytoalexins.
Stephen M. Boue, Carol H. Carter, Kenneth C. Ehrlich and Thomas E. Cleveland,Southern Regional Research Center, USDA, New Orleans, LA 70124
4. Phytochemical Glyceollins, Isolated From Soy, Mediate Anti-Hormonal Effects Through Estrogen Receptor Alpha And Beta
Matthew E. Burow, Steve Boue, Bridgette M. Collins-Burow, Lilia I. Melnik, Bich N. Duong, Tom Weiss, Ed Cleavland, John A. McLachlan.
Environmental Endocrinology Project at the Tulane-Xavier Center for Bioenvironmental Research
Molecular and Cellular Biology Program, Department of Pharmacology, Tulane University Medical Center
Department of Environmental Health Sciences, Tulane University School of Public Health and Tropical Medicine
School of Pharmacy at Xavier University
The Southern Research Center, United States Department of Agriculture, New Orleans, Louisiana 70112
5. Immunohistochemical Detection Of Vitellogenin (Vg) In Formalin-Fixed Livers Of Lepomis macrochirus.
Burse, Jeanine R.1, Ann O. Cheek2, and Henry L. Bert Jr.1.
1Ecology, Evolution, and Organismal Biology Dept., Tulane University, New Orleans, LA 70118 and
2Dept. of Biology, Southeastern University of Louisiana, Hammond, LA 70402
6. In Vivo Effects of Cadmium on the Estrogen Signaling Pathway During Spermatogenesis.
Gloria V. Callard*, Chunhua Wang, Roshana Sikora, and Marlies Betka
Department of Biology, Boston University, Boston MA 02215
7. Identification of phthalate esters in the serum of young Puerto Rican girls with premature breast development (thelarche)
Ivelisse Colón1, Doris Caro1, Osvaldo Rosario1, Carlos J. Bourdony
1Department of Chemistry, University of Puerto Rico, San Juan, Puerto and
2 Premature Sexual Development Registry of Puerto Rico, Department of Health Pediatric Endocrinology Division, San Juan City Hospital, Puerto Rico Department of Pediatrics, University of Puerto Rico, School of Medicine
8. A cDNA From The Fresh Water Mussel (Elliptio complanata) With Homology To Vertebrate Steroid Receptors.
Noemi Custodia, Seung Jae Won, and Ian P. Callard
Department of Biology, Boston University, Boston, MA 02215
9. Biomarkers For Exposure to Environmental Estrogens.
W. Dean-Colomb1 and E. Jeffery2.
1Dept of Veterinary Biosciences and 2Dept of Food Science and Human Nutrition. University of Illinois, Urbana-Champaign.
10. Phytoestrogen Signaling: Insights From Plant/Bacteria Symbiosis.
Fox, J., Kow, K., Burow, M., Starcevic, M., McLachlan, J.
Molecular and Cellular Biology Program and Environmental Endocrinology Project at the Tulane-Xavier Center for Bioenvironmental Research, New Orleans LA 70112
11. Bisphenol A Is Released From Used Polycarbonate Rodent Cages.
KL Howdeshell, PH Peterman, RL Ruhlen, BM Judy, WV Welshons and FS vom Saal,
University of Missouri and Columbia Environmental Research Center (USGS), Columbia, MO 65211
12. Estrogenic Effects Of Bisphenol A In Mice Following In Utero And Post-natal Exposure.
Caroline Markey, Cheryl Michaelson, Electra Veson, Carlos Sonnenschein & Ana Soto,
Department of Anatomy and Cellular Biology, Tufts University School of Medicine, 136 Harrison Ave, Boston MA 02111-1800.
13. Georgi N. Nikov1, Nancy E. Hopkins*2, Stephen Boue3 and William L. Alworth*1
1 Tulane University, New Orleans, LA 70118,USA
2 Millsaps College, Jackson, MS 39210, USA
3 Southern Regional Research Center, U.S.D.A., New Orleans, LA 70124, USA
14. Applications Of In Vivo Tests For Estrogen Effects In The Reed Frog Hyperolius Argus.
N.C. Noriega* and T.B. Hayes.
University of California, Berkeley.
15. Aromatase Activity In The Ovary Of Mosquitofish Gambusia Holbrooki, Collected From The Fenholloway And Econfina Rivers, Florida.
Edward F. Orlando1, William P. Davis2, Lisa Catabiano1, Danielle Bass1,and Louis J. Guillette, Jr.1
1Department of Zoology, University of Florida, Gainesville 32611
Tele: 352+392-1098, Email: firstname.lastname@example.org
2EPA Gulf Ecology Division, 1 Sabine Island Drive, Gulf Breeze, Florida 32561
16. The Regulation of Barbiturate-mediated Induction of CYP 102 by Xeno- and Phytoestrogens : Possible intersection of signalling pathways in primitive systems.
Rajendram V Rajnarayanan, Christopher W Rowley and William L Alworth
Department of Chemistry , Tulane University, New Orleans 70118
and Tulane / Xavier Center for Bioenvironmental Research, New Orleans, LA 70112
17. Fetal Exposure To Very Low Doses Of Ethinyl Estradiol Increases Prostate Size And Androgen Receptors In CF-1 And CD-1 Mice.
RL Ruhlen, KA Thayer, DE Preziosi, KL Howdeshell, WV Welshons, FS vom Saal,
University of Missouri (Columbia), Columbia MO 65211
18. A Low Dose Effect Of Environmental Endocrine Disruptors On Female Mouse Thymus, With Special Reference To T Cell Apoptosis.
Kou Sakabe, Fujio Kayama, Takahiko Yoshida, Hiroyuki Aikawa
Department of Morphology, Tokai University School of Medicine, Isehara, Kanagawa, JapanÅiKS)
Department of Environmental Health, Jichi Medical School, Kawachi, Tochigi, JapanÅiFK)
Department of Environmental Health, Tokai University School of Medicine, Isehara, Kanagawa, JapanÅiTY & HA)
19. Vitellogenin As A Biomarker For Estrogenic Chemicals: Develoment Of Antibodies And Primers With Broad Species Applications
.Kyle Selcer, Phil Foret, Jodi Danyo, Danielle Wagner and Brent Palmer
Department of Biological Sciences, Duquesne University, Pittsburgh, PA and Department of Biology, University of Kentucky, Lexington, KY.
20. Bisphenol A Bioaccumulates In The Serum Of Pregnant Mice.
Julia A. Taylor*, Barbara M. Judy*, Brian A. Rottinghaus*, Kellee J. Blackwell*, George E. Rottinghaus*, Leanne C. Alworth**, Frederick S. vom Saal** and Wade V. Welshons*
*Department of Veterinary Biomedical Sciences and **Division of Biological Sciences, University of Missouri-Columbia, Columbia, MO 65211-5120.21.
Environmental Estrogens and Breast Cancer Therapeutics: Characterization Of The Diverse Ligand Binding Properties Of The Estrogen Receptor.
Dana E. Warn and Deborah S. Wuttke,
Department of Chemistry and Biochemistry, University of Colorado at Boulder, Boulder, CO 80309-0215, USA.
22. Gonadal Development In The Japanese Medaka (Oryzias latipes) As A Model For Estrogenic Potency Determination.
Mingyi Wen,12 Arunthavarani Thiyagarajah, A.,12 Mary B. Anderson,3 and William R. Hartley12
1 Department of Environmental Health Sciences, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA.
2 Center for Bioenvironmental Research, Tulane and Xavier University, New Orleans, LA.
3 Department of Anatomy, School of Medicine, Tulane University Medical Center, New Orleans, LA.
23. Aroclor 1242 Alters Aromatase Activity During Embryogenesis In The Red-Eared Slider Turtle, A Species With Temperature-Dependent Sex Determination.
Emily Willingham and David Crews,
Institute of Reproductive Biology, The University of Texas at Austin, Austin, TX, 78712
24. Organochlorine Compounds And Menstrual Cycle Function.
Gayle C. Windham, Diana Lee, Gina Margillo, Kirsten Waller, Shanna Swan, Bill Lasley
California Department of Health Services, Univeristy of California, Davis and University of Missouri
25. Yolk Protein Synthesis In Caenorhabditis elegans: Potential Regulation By Estrogens?
Seung-Jae Won, Mark Wieland, Chris Li, and Ian P. Callard
Department of Biology, Boston University, Boston, MA 02215